MANGOSTEEN EXTRACT POWDER - NexTive® MANGOSTIN P DP

Mangosteen peel (Garcinia mangostana L.) is a valuable natural medicinal material that has been used for centuries in traditional medicine across Southeast Asian countries, including Vietnam, Thailand, Malaysia, and Indonesia. Traditionally, mangosteen peel has been used to treat gastrointestinal disorders such as diarrhea and dysentery, as well as externally for its antiseptic properties and to promote the healing of wounds and skin ulcers.

Mangosteen peel contains a wide range of valuable bioactive compounds, including xanthones, tannins, flavonoids, polyphenols, and anthocyanins, which contribute to its remarkable antioxidant properties. These compounds help neutralize free radicals, protect skin cells against DNA damage, and prevent premature aging caused by UV radiation and environmental pollution. As a result, mangosteen peel extract may help maintain the skin's structural integrity, reduce the appearance of wrinkles, and promote a youthful, healthy-looking complexion.

Among these bioactive compounds, xanthones are considered the most prominent and important group, particularly α-mangostin. Scientific studies have demonstrated that α-mangostin exhibits the potential to inhibit collagen-degrading enzymes such as MMP-1 and MMP-9 while stimulating endogenous collagen production. Furthermore, these compounds exhibit potent anti-inflammatory properties by modulating the NF-κB and MAPK signaling pathways, helping reduce inflammatory responses and protect the skin against oxidative stress.

Scientific studies have also highlighted the potential of mangosteen peel extract in acne management due to its direct antibacterial activity against bacteria such as Cutibacterium acnes and Staphylococcus epidermidis. Additionally, α-mangostin shows promising skin-brightening and tone-evening potential through the inhibition of the enzyme tyrosinase, thereby helping reduce melanin synthesis associated with hyperpigmentation, dark spots, and freckles.